~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ The Raelian Movement for those who are not afraid of the future : http://www.rael.org ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Read more: http://www.dailymail.co.uk/sciencetech/article-2129200/Could-cure-AIDS-horiz on-Genetically-engineered-human-stem-cells-hunt-kill-HIV-inside-body.html#ix zz1s7dJ7O3d Could a cure for AIDS be on the horizon? Genetically engineered human stem cells can hunt down and 'kill' HIV inside the body PUBLISHED: 09:56 GMT, 13 April 2012 | UPDATED: 09:56 GMT, 13 April 2012 Human stem cells can be genetically engineered into 'warrior' cells that fight HIV - and the new cells can attack HIV-infected cells inside a living creature. The breakthrough, by UCLA scientists, is hoped to be the first step towards a treatment that can eradicate HIV from an infected patient. Much HIV research focuses on vaccines or drugs that slow the virus's progress - but this new technique could offer hope of a 'cure'. The study, published April 12 in the journal PLoS Pathogens, demonstrates for the first time that engineering stem cells to form immune cells that target HIV is effective in suppressing the virus in living tissues. 'We believe that this study lays the groundwork for the potential use of this type of an approach in combating HIV infection in infected individuals, in hopes of eradicating the virus from the body,' said lead researcher Scott G Kitchen. The scientists took CD8 cytotoxic T lymphocytes - the 'killer' T cells that help fight infection - from an HIV-infected individual and identified the molecule which guides the T cell in recognizing and killing HIV-infected cells. However, these T cells, while able to destroy HIV-infected cells, do not exist in great enough quantities to clear the virus from the body. So the researchers cloned the receptor and used this to genetically engineer human blood stem cells. They then placed the engineered stem cells into human thymus tissue that had been implanted in mice, allowing them to study the reaction in a living organism. The engineered stem cells developed into a large population of mature, multi-functional HIV-specific cells that could specifically target cells containing HIV proteins. The researchers also discovered that HIV-specific T cell receptors have to be matched to an individual in much the same way an organ is matched to a transplant patient. In this current study, the researchers similarly engineered human blood stem cells and found that they can form mature T cells that can attack HIV in tissues where the virus resides and replicates. They did so by using a surrogate model, the humanized mouse, in which HIV infection closely resembles the disease and its progression in humans. In a series of tests on the mice's peripheral blood, plasma and organs conducted two weeks and six weeks after introducing the engineered cells, the researchers found that the number of CD4 "helper" T cells - which become depleted as a result of HIV infection - increased, while levels of HIV in the blood decreased. 'We believe that this is the first step in developing a more aggressive approach in correcting the defects in the human T cell responses that allow HIV to persist in infected people,' Kitchen said. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ WARNING FROM RAEL: For those who don't use their intelligence at its full capacity, the label "selected by RAEL" on some articles does not mean that I agree with their content or support it. "Selected by RAEL" means that I believe it is important for the people of this planet to know about what people think or do, even when what they think or do is completely stupid and against our philosophy. When I selected articles in the past about stupid Christian fundamentalists in America praying for rain, I am sure no Rael-Science reader was stupid enough to believe that I was supporting praying to change the weather. So, when I select articles which are in favor of drugs, anti-semitic, anti-Jewish, racist, revisionist, or inciting hatred against any group or religion, or any other stupid article, it does not mean that I support them. It just means that it is important for all human beings to know about them. Common sense, which is usually very good among our readers, is good enough to understand that. When, like in the recent articles on drug decriminalization, it is necessary to make it clearer, I add a comment, which in this case was very clear: I support decriminalizing all drugs, as it is stupid to throw depressed and sad people (as only depressed and sad people use drugs) in prison and ruin their life with a criminal record. That does not mean that there is any change to the Message which says clearly that we must not use any drug except for medical purposes. The same applies to the freedom of expression which must be absolute. That does not mean again of course that I agree with anti-Jews, antisemites, racists of any kind or anti-Raelians. But by knowing your enemies or the enemies of your values, you are better equipped to fight them. With love and respect of course, and with the wonderful sentence of the French philosopher Voltaire in mind: "I disapprove of what you say, but I will defend to the death your right to say it". -- ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ "Ethics" is simply a last-gasp attempt by deist conservatives and orthodox dogmatics to keep humanity in ignorance and obscurantism, through the well tried fermentation of fear, the fear of science and new technologies. There is nothing glorious about what our ancestors call history, it is simply a succession of mistakes, intolerances and violations. On the contrary, let us embrace Science and the new technologies unfettered, for it is these which will liberate mankind from the myth of god, and free us from our age old fears, from disease, death and the sweat of labour. Rael ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Tell your friends that they can subscribe to this list by sending an email to: subscribe@rael-science.org - - - To unsubscribe, send an email to: unsubscribe@rael-science.org - - -
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