[rael-science] Artificial Liver to Replace Animal Testing‏

วันศุกร์ที่ 16 พฤศจิกายน พ.ศ. 2555

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The Raelian Movement
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Source: http://www.alnmag.com/news/artificial-liver-replace-animal-testing

Artificial Liver to Replace Animal Testing

News Posted: November 13, 2012
Courtesy of Colin Hattersley
Courtesy of Colin Hattersley
Scientists at Heriot-Watt Univ. are working towards creating the world’s first artificial human livers for drug testing to drastically cut the number of live animals used and get life-saving medicines into the clinic faster.
Dr. Will Shu is leading the Heriot-Watt Univ. team in the £100,000 project. Working closely with Roslin Cellab, the team aims to demonstrate how an artificial liver, created using human cells, could become a new testing platform for drug discovery and development.
The team is working towards creating miniature human liver tissues and, eventually, "livers-on-a-chip," using novel technology that will "print" the cells in 3D onto testing surfaces.
Shu says, “If we are able to advance this technique, the medical benefits could be enormous.”
Testing new drugs currently requires large numbers of experimental animals. This work is expensive, time-consuming and is often inconclusive since drugs that pass animal testing usually fail during the even more expensive clinical stages of development, when the first human subjects are used.
Dr. Jason King of Roslin Cellab says, “If successful, this technology will enable drug developers to test using human organ models at a much earlier stage. It should highlight drug failures well before they reach the clinic and help target resources towards the most promising new drug candidates.”
There is growing interest in the cell-printing technique from scientists internationally because 3D cells, such as those being developed by Shu’s team, outperform cells grown in 2D cultures, which until now have been the standard in the drug development sector.

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"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
 
There is nothing glorious about what our ancestors call history, 
it is simply a succession of mistakes, intolerances and violations.
 
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
 
Rael
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