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The Raelian Movement
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Source: http://www.alnmag.com/news/humans-chimpanzees-and-monkeys-share-dna-not-gene-regulatory-mechanisms
Humans share over 90 percent of their DNA with their primate cousins. The expression or activity patterns of genes differ across species in ways that help explain each species' distinct biology and behavior.
for those who are not afraid of the future : http://www.rael.org
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Source: http://www.alnmag.com/news/humans-chimpanzees-and-monkeys-share-dna-not-gene-regulatory-mechanisms
Humans, Chimpanzees and Monkeys Share DNA but Not Gene Regulatory Mechanisms
News Posted: November 08, 2012Humans share over 90 percent of their DNA with their primate cousins. The expression or activity patterns of genes differ across species in ways that help explain each species' distinct biology and behavior.
DNA factors that contribute to the differences were described at the American Society of Human Genetics 2012 meeting in a presentation by Yoav Gilad, associate professor of human genetics at the Univ of Chicago.
Gilad reported that up to 40 percent of the differences in the expression or activity patterns of genes between humans, chimpanzees and rhesus monkeys can be explained by regulatory mechanisms that determine whether and how a gene's recipe for a protein is transcribed to the RNA molecule that carries the recipe instructions to the sites in cells where proteins are manufactured.
In addition to improving scientific understanding of the uniqueness of humans, studies such as the investigation conducted by Gilad and colleagues could have relevance to human health and disease.
"Through inter-species' comparisons at the DNA sequence and expression levels, we hope to identify the genetic basis of human specific traits and in particular the genetic variations underlying the higher susceptibility to certain diseases such as malaria and cancer in humans than in non-human primates," says Gilad.
Gilad and his colleagues studied gene expression in lymphoblastoid cell lines, laboratory cultures of immortalized white blood cells, from eight humans, eight chimpanzees and eight rhesus monkeys.
They found that the distinct gene expression patterns of the three species can be explained by corresponding changes in genetic and epigenetic regulatory mechanisms that determine when and how a gene's DNA code is transcribed to a messenger RNA (mRNA) molecule.
Gilad also determined that the epigenetics process known as histone modification also differs in the three species. The presence of histone marks during gene transcription indicates that the process is being prevented or modified.
"These data allowed us to identify both conserved and species-specific enhancer and repressor regulatory elements, as well as characterize similarities and differences across species in transcription factor binding to these regulatory elements," Gilad says.
Among the similarities among the three species were the promoter regions of DNA that initiated transcription of a particular gene.
In all three species, Dr. Gilad's lab found that transcription factor binding and histone modifications were identical in over 67 percent of regulatory elements in DNA segments that are regarded as promoter regions.
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"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
There is nothing glorious about what our ancestors call history,
it is simply a succession of mistakes, intolerances and violations.
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
Rael
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